For a fully updated list of publications, check out Juan’s Google Scholar profile.

(co-)first author

(co-)corresponding author


Towards synthetic ecology: strategies for the optimization of microbial community functions

Magdalena San Román*, Andrea Arrabal*, Belen Benitez-Dominguez*, Isabel Quirós-Rodríguez*, Juan Diaz-Colunga*

Frontiers in Synthetic Biology 3:1532846 (2025)

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Global epistasis and the emergence of function in microbial consortia

Juan Diaz-Colunga*, Abigail Skwara*, Jean CC Vila, Djordje Bajic, Álvaro Sánchez

Cell 187:1-12 (2024)

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Full factorial construction of synthetic microbial communities

Juan Diaz-Colunga*, Pablo Catalan*, Magdalena San Roman*, Andrea Arrabal*, Alvaro Sanchez*

eLife 13:RP101906 (2024)

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Global epistasis in plasmid-mediated antimicrobial resistance

Javier DelaFuente*, Juan Diaz-Colunga*, Álvaro Sánchez, Álvaro San Millan

Molecular Systems Biology 20(4):311–320 (2024)

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The optimization of microbial functions through rational environmental manipulations

Álvaro Sánchez, Andrea Arrabal, Magdalena San Román, Juan Diaz-Colunga

Molecular Microbiology 00:1–10 (2024)

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Environmental modulation of global epistasis in a drug resistance fitness landscape

Juan Diaz-Colunga*, Álvaro Sánchez, C. Brandon Ogbunugafor

Nature Communications 14:8055 (2023)

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Statistically learning the functional landscape of microbial communities

Abigail Skwara, Karna Gowda, Mahmoud Yousef, Juan Diaz-Colunga, Arjun S. Raman, Álvaro Sánchez, Mikhail Tikhonov, Seppe Kuehn

Nature Ecology & Evolution 7(11):1823–1833 (2023)

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Global epistasis on fitness landscapes

Juan Diaz-Colunga*, Abigail Skwara*, Karna Gowda*, Ramón Díaz-Uriarte*, Mikhail Tikhonov*, Djordje Bajic*, Álvaro Sánchez*

Philosophical Transactions of the Royal Society B 378:20220053 (2023)

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The community-function landscape of microbial consortia

Álvaro Sánchez*, Djordje Bajic*, Juan Diaz-Colunga*, Abigail Skwara*, Jean CC Vila*, Seppe Kuehn*

Cell Systems 14(2):122–134 (2023)

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Predictability of the community-function landscape in wine yeast ecosystems

Javier Ruiz*, Miguel de Celis*, Juan Diaz-Colunga, Jean CC Vila, Belén Benítez-Domínguez, Javier Vicente, Antonio Santos, Álvaro Sánchez, Ignacio Belda

Molecular Systems Biology 19(9):e11613 (2023)

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Top-down and bottom-up cohesiveness in microbial community coalescence

Juan Diaz-Colunga*, Nanxi Lu*, Alicia Sánchez-Gorostiaga*, Chang-Yu Chang, Helen S. Cai, Joshua E. Goldford, Mikhail Tikhonov, Álvaro Sánchez

Proceedings of the National Academy of Sciences 119(6):e2111261119 (2022)

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Diversity begets diversity under microbial niche construction

Sylvie Estrela*, Juan Diaz-Colunga*, Jean CC Vila, Alicia Sánchez-Gorostiaga, Álvaro Sánchez

bioRxiv (2022)

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Engineering complex communities by directed evolution

Chang-Yu Chang*, Jean CC Vila*, […], Juan Diaz-Colunga, Sylvie Estrela, María Rebolleda-Gómez, Álvaro Sánchez

Nature Ecology & Evolution 5(7):1011–1023 (2021)

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Directed evolution of microbial communities

Álvaro Sánchez, Jean CC Vila, Chang-Yu Chang, Juan Diaz-Colunga, Sylvie Estrela, María Rebolleda-Gómez

Annual Review of Biophysics 50:323–341 (2021)

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Conditional prediction of consecutive tumor evolution using cancer progression models: What genotype comes next?

Juan Diaz-Colunga, Ramón Díaz-Uriarte

PLOS Computational Biology 17(12):e1009055 (2021)

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Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation

Ana F. Lima, Gillian May, Juan Diaz-Colunga, Susana Pedreiro, Artur Paiva, Luciana Ferreira, Tariq Enver, Francisco J. Iborra, Ricardo Pires das Neves

Scientific Reports 8(1):1–14 (2018)

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Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression

Silvia Márquez-Jurado*, Juan Diaz-Colunga*, Ricardo Pires das Neves, Antonio Martínez-Lorente, Fernando Almazán, Raúl Guantes, Francisco J. Iborra

Nature Communications 9(1):1–11 (2018)

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Epigenetic control of influenza virus: role of H3K79 methylation in interferon-induced antiviral response

Laura Marcos-Villar, Juan Diaz-Colunga, Juan Sandoval, Noelia Zamarreño, Sara Landeras-Bueno, Manel Esteller, Ana Falcón, Amelia Nieto

Scientific Reports 8(1):1–13 (2018)

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Mitochondria and the non-genetic origins of cell-to-cell variability: more is different

Raúl Guantes, Juan Diaz-Colunga, Francisco J. Iborra

BioEssays 38(1):64–76 (2016)

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